Endocrine Abstracts

Introduction: Thyrotropinomas are usually considered when the TSH level is inappropriately elevated or normal in a hyperthyroid patient with increased serum T4 levels, regardless of the presence of visible tumor on imaging. The prevalence of these adenomas, which account for 0.5–3% of all pituitary tumors has been estimated to be around one case per million. Most thyrotroph adenomas are large and invasive at diagnosis, and present with signs and symptoms of an ...

Introduction: Parathyroid adenomas appear typically as homogeneous, hypoechoic lesions compared to the thyroid on the ultrasonography examination. They can be detected easily when they are more than 1 cm. However, cystic parathyroid adenomas are rare. When present, they appear as decreased echogenic areas in the gland. Extrathyroidal feeding from an artery at one pole of the gland is characteristic which is seen on Doppler imaging. We aimed to present a case series including s...

Background and aim: In the general population, the frequency of thyroid micronodules is increasing and the prevalence of malignancy is higher in nodules at this size. The ultrasonographic features of these nodules are neither spesific nor sensitive Elastography gives information about the degree of hardness at the tissue level and provides assessment of malignancy risk of the nodule. The aim of the study was to investigate the diagnostic value of elastography in patients with ...

Introduction: Polycystic ovary syndrome (PCOS) is a common endocrinopathy associated with increased cardiovascular risk in reproductive aged women. Circulating osteoprotegerin (OPG) and soluble receptor activator of nuclear factor κB ligand (sRANKL) are associated with subclinical atherosclerosis. Our aim is to evalutate serum OPG and sRANKL levels and their relations with cardiovascular and metabolic markers in paients with obese and non-obese PCOS.<p class="abstext"...

Introduction: Patients with parathyroid carcinoma (PCA) and synchronous disease in other parathyroid glands have been reported in the literature. Here, we report a patient who had persistant hypercalcemia after operated from parathyroid carcinoma and improvement of hypercalcemia after the subsequent operation from atypically localised parathyroid adenoma.Case report: A 62-year-old man presented with a history of headache, fatigue, and nervousness. Labora...

Background: Primary hyperparathyroidism (PHPT) is one of the most common endocrine diseases. Parathyroid carcinoma, a rare entity, comprises a small percentage of patients with hyperparathyroidism and represents 0.005% of all cancers and <1% of cases of PHPT.Material and methods: Patients was diagnosed at the Endocrinology Department of Diskapi Yildirim Beyazit Training and Research Hospital between 2010 and 2016. Ultrasound and 99mTc-Sestamibi confi...

Background and aim: The risk for breast cancer in patients with thyroid cancer has been investigated in previous studies, and has been found to be increased. In this study we, therefore present retrospective analysis of the patients with differentiated thyroid carcinoma in respect to breast cancer and family history for breast cancer.Methods: We conducted a retrospective study involving 455 patients with a diagnosis of differentiated thyroid carcinoma be...

Introduction: Thyroid incidentaloma detected by FDG-PET/CT (flourodeoxyglucose positron emition tomography/computed tomography) is important because of high rate of malignancy. Elastosonograpghy has proven valuable in discriminating malign and benign thyroid lesions. In this study, we aimed to evaluate PET incidentalomas by ultrasonography and elastosonography and to compare cytopathological results with imaging findings.Methods: A total of 50 patients i...

Introduction: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women of reproductive age. A disintegrin and metalloproteinase with thrombospondin-like motifs (ADAMTS) are involved in inflammation and fertility. The aim of this investigation was to evaluate to serum levels of ADAMTS1, ADAMTS5, ADAMTS9, IL17, IL23, IL33 and to find out the relationship between these inflammatory cytokines and ADAMTSs in PCOS patients.Met...

Aims: Primary hyperparathyroidism (PH) has been reported to be associated with increased insulin resistance, hypertension, dyslipidemia and cardiovascular inflammatory markers. The aims of this study were to evaluate the rate of metabolic syndrome (MS) and effect of parathormone, calcium and phosphorus levels to MS components in PH subjects.Methods: One hundred and fifty one subjects, 23 men and 128 women, aged 53±11.2 years with newly diagnosed PH ...